Specialty Laboratories Presents: Active B12; The next level of B12 testing Learn why it is important to test for active B12 in the management of patients with vitamin B12 deficiency. Vitamin B12 deficiency can lead to a wide spectrum of hematologic and neuropsychiatric disorders that can often be reversed by early diagnosis and prompt treatment. Total serum vitamin B12 may not reliably indicate vitamin B12 status because 70-80% of the total is not available for cell uptake. Active B12 measurement has improved the sensitivity and specificity for detecting vitamin B12 deficiency. FREE Live CME Web Conference (Registration required) Please click the link below to complete the required registration. Register December 13th Eastern Central Mountain Pacific Noon 11am 10am 9am After you have registered, you will receive an email confirmation. This message will provide the information you need to join the meeting. Registration: All participants are required to register on the WebEx site prior to the program. A link to the WebEx registration site is available on the Specialty Website (www.specialtylabs.com) under the CME Hot Button. Once registered, participants can log on to the program. Registration should be done as soon as possible. If you have questions call: 1-800-421-7110 ext. 6696 Special thanks to Abbott and Axis Shield for support of this program.

At the end of the program, participants will be able to describe the clinical presentation of patients with vitamin B12 deficiency, the physiology of the B12-binding proteins and the clinical utility of tests to diagnose B12 deficiency with special reference to active B12. 1 hour of free CME credit will be provided Who should attend: Physicians, laboratorians and other healthcare professionals interested in B12 deficiency Ralph Green, MD, PhD, FRCPath Professor and Chair, Department of Pathology and Laboratory Medicine. University of California, Davis

* Henry Mayo Newhall Memorial Hospital (HMNMH) is accredited by the Institute of Medical Quality/California Medical Association (IMQ/CMA) to provide continuing medical education for physicians. HMNMH takes responsibility for the content, quality, and scientific integrity of this CME activity. HMNMH designates this educational activity for a maximum of 1 AMA PRA Category 1 credit™. Physicians should claim credit commensurate with the extent of their participation in the activity. This credit may also be applied to the CMA Certification in Continuing Medical Education.