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Celiac Disease (CD) affects over
3 million in the U.S., and is one of the most under-diagnosed
diseases in the world. The genetic inheritance to CD is strongly
associated with HLA-DQ2 and HLA-DQ8.1 More than 97% of patients
with CD have one or both genetic markers.1 When both markers are
negative it is very unlikely that CD is present. HLA testing is
not a screening test for CD; rather, the value of the test lies
in the ability to exclude disease when a negative result occurs.
- Aid in ruling-out CD in patients with indeterminate serological
results
- A patient negative for DQ2 and DQ8 is extremely unlikely to
have CD
- Aid in excluding CD in at-risk populations
- Helps rule-out CD in family members who are negative for serology
- Our comprehensive menu includes tests recommended by the NIH
for complete diagnosis or rule-out of CD1
For more information, you may refer to the documents on the right
or contact Client Services at 800-421-4449.
References
- NIH Consensus Development Conference Statement on Celiac
Disease. consensus.nih.gov/2004/2004CeliacDisease118html.htm
Accessed on August 16, 2005.
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