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Women's Health
10969: ER/PR/DNA/HER2 w/Reflex to HER2 FISH, Paraffin Block Print View
Paraffin Block Number:      
Primary Tumor Site:      
Quest Internal Number:      
Estrogen Receptor COLORIMETRIC    % 
ER Staining Intensity IHC     
ER Interpretation      
Progesterone Receptor     % 
PR Staining Intensity IHC     
PR Interpretation      
DNA Index/Ploidy FC     
DNA Prognostic Category CIA     
S-Phase Fraction FC    % 
SPF Prognostic Category CIA     
Sample Fixed In Formalin?      
Fixed Between 6-48 Hours?      
Routine Tissue Processing?      
Staining Intensity IHC     
HER2 Overexpression      

PRIMARY
1 Tissue Paraffin Block   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  
ALTERNATE
  4um unst sect % 50um shav   Room Temperature - 12 Month(s)  

Estrogen and progesterone receptor assays are routinely performed on breast carcinomas to assess responsiveness to endocrine therapy and and prognosis. DNA Analysis is used to estimate tumor aggressiveness and patient prognosis. HER-2 is associated with cellular proliferation activity. Overexpression is observed in 25-30% of women with breast cancer. These patients are potential candidates for for monoclonal therapy.

Please submit stained H & E slide and a copy of the pathology report.
Ship at room temperature. Do not place paper labels with adhesive
backing on slides. Use pencil or xylene resistant pen to write on the
frosted end of the slide only. Invasive or metastatic breast cancer
formalin-fixed paraffin embedded tissue or charged/+slides from
formalin-fixed paraffin embedded tissue. Specimen MUST be fixed in 10%
neutral buffered formalin. Fixation between 6 and 48 hours is
recommended. Pathology report must accompany paraffin block or slides.
Information required in this report include: Physician identification,
specimen identifiers (case and block number), specimen site and type,
tissue processing used (routine or microwave), type of fixative, time
and duration of fixation, pathologic diagnosis, and IHC score, if
performed elsewhere. Ship at room temperature. Do not freeze.
Setup Schedule
Monday-Friday

Reported (Analytical Time)
7 days

CPT Codes
88360x3,88182

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: Non-invasive tumors Alternate Specimen: 4 micron unstained sections and 50 micron shavings






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