C.trachomatis infections are the leading cause of sexually transmitted diseases in the United States. C. trachomatis is known to cause cervicitis, pelvic inflammatory disease (PID), epididymitis and proctitis. It is also the most frequent cause of non-gonococcal urethritis in men. Among women, the consequences of chlamydial infections are severe if left untreated. Approximately half of chlamydial infections are asymptomatic.
Labs performing cytology: Aliquot PreservCyt(R) or SurePath(R)
solution before performance of liquid based cytology testing.
PreservCyt(R): Transfer 1 mL of PreservCyt(R) solution into
APTIMA(R) Specimen Transfer Tube (green label) or APTIMA(R) Vaginal
Collection or Multi-Test Collection (orange label). Ship to lab.
SurePath(R): SurePath(R) fluid must be transferred to APTIMA(R) STM
within 4 days of collection. Transfer 0.5 mL of SurePath
preservative fluid to APTIMA(R) Specimen Transfer Tube
(green label) or APTIMA(R) Vaginal Collection or Multi-Test
Collection (orange label) Ship to lab.
Endocervical or urethral swabs: Follow instructions in the
APTIMA(R) Combo 2 Assay Unisex Swab Specimen Collection Kit.
In females, to ensure collection of cells infected with
C. trachomatis, columnar epithelial cells lining the
endocervix should be obtained. To that effect, excess mucus
should be removed prior to sampling.
Vaginal swabs: Follow instructions in the APTIMA(R) Combo 2
Assay Vaginal Swab Collection or Multi-Test Collection Kit.
Urine: Patient should not have urinated within one hour
prior to collection. Female patients should not cleanse
the labial area prior to providing the specimen. Direct
patient to provide a first-catch urine
(a maximum 0f 20-30 mL of the initial urine stream) into a
urine collection cup free of any preservatives. 2 mL of urine
specimen must be transferred into the APTIMA(R) Specimen
Transport within 24 hours of collection and before being
assayed. Use tube provided in the urine specimen collection
kit for urine specimens. The fluid (urine plus transport
media) level in the urine transport tube must fall within
the clear pane on the tube label.
Reported (Analytical Time)
The CPT codes provided are based on AMA guidelines and are for informational purposes only.
CPT coding is the sole responsibility of the billing party.
Please direct any questions regarding coding to the payer being billed.
Transport Temperature: Room Temperature Reject Criteria: Transport tubes with 2 swabs; transport tubes with non-APTIMA(R) swabs; specimens in broken containers; swab submitted in M4 transport media. Methodology: Target Capture, Transcription-Mediated Amplification, and Dual Kinetic Assay. Preferred Specimen: Aptima Vaginal Collection or Multi-Test Collection