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16838: Histamine Release (Chronic Urticaria) Print View
Histamine Release   < 16  % 

PRIMARY
1 Serum 1.5 (1) mL   Frozen - 30 Day(s)/Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)  
ALTERNATE

Chronic urticaria (CU) is a common skin disorder affecting 1 to 6% of the general population. It is characterized by repeated occurrence of short-lived cutaneous wheals accompanied by redness and itching. Autoimmune urticaria is defined by the presence of a functional IgG antibody to high-affinity IgE receptor (Fc epsilon RI alpha) or IgE. These antibodies trigger mast cell and basophil degranulation by the engagement of Fc epsilon receptor. Functional IgG antibody to the receptor has been identified in approximately 30-40% of patients with CU, and anti IgE antibody has been identified in another 5% to 10%.

Patients taking calcineurin inhibitors should stop their medication
for 72 hours prior to draw.
Setup Schedule
Tuesday, Thursday

Reported (Analytical Time)
4-9 days

CPT Code
86343

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
METHODOLOGY: Cell Culture and Immunoassay Reject Criteria: Gross hemolysis, lipemic or icteric specimen; Sample other than serum; SST






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