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16986: Fascin, IHC without Interpretation Print View
Paraffin Block Number:      
Primary Tumor Site:      
Quest Internal Number:      
Fascin, IHC w/o interp      
Slides/Block Mailed on:      

PRIMARY
1 Tissue Paraffin Block   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  
ALTERNATE
  Slides Unstained charged   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  

Anti-Fascin is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin is present in dendritic cells. This marker may be helpful in distinguishing between Hodgkin's disease and non-Hodgkin's lymphoma in difficult cases. Also, the lack of expression of fascin in the neoplastic follicles in follicular lymphoma can be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Fascin has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung, as well as ovarian cancer.
Setup Schedule
Monday-Saturday

Reported (Analytical Time)
Same day

CPT Code
88342+TC

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
REJECT CRITERIA: Tissue in fixative






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