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19955: Celiac Disease Comprehensive Panel Print View
Interpretation      
(tTG) Ab, IgA IA  < 4  U/mL 
IgA, Serum IM  view ref range  mg/dL 

PRIMARY
1 Serum 5 (1) mL   Room Temperature - 72 Hour(s)/Refrigerated - 7 Day(s)/Frozen - 21 Day(s)  
ALTERNATE

Celiac disease is caused by an immune response to gluten in genetically sensitive individuals. The diagnosis is largely based on a biopsy of the small intestine, but serologic tests also help support a diagnosis and may assist identification of patients who may require biopsy. Tissue transglutaminase antibodies (tTG, IgA) is a marker with 95% sensitivity and specificity. Total IgA is measured because 2-3% of celiac disease patients are IgA deficient. Because tTG, IgA, and anti-Gliadin IgA tend to decrease in patients on a gluten-free diet, these markers are also used to assess dietary compliance. The endomysial antibody (EMA, IgA) assay has high specificity for celiac disease and is used to confirm positive anti-tTG results.
Setup Schedule
Sunday-Saturday

Reported (Analytical Time)
Same day

CPT Codes
82784,83516

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Immunoassay; ImmunoTurbidimetric Reject Criteria: Gross hemolysis; grossly lipemic Transport Tempereature: Refrigerated Additional Information: If the Transglutaminas IgA is positive, then Endomysial Antibody Screen (IgA) will be performed at an additional charge. If the Endomysial Antibody Screen (IgA) is positive, then Endomysial Antibody Titer will be performed at an additional charge. If the total IgA is less than the lower limit of the reference range, based on age, then Tissue Transglutaminase IgG will be performed at an additional charge.






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