Thyroglobulin (Tg) is a secretory product only of the thyroid gland. The major clinical use of serum Tg measurement is to monitor, but not to diagnose, patients with well-differentiated thyroid cancers. The measurement of thyroglobulin, after thyroidectomy and ablation of the thyroid gland, is useful to determine metastasis. Deficient Tg synthesis is observed in infants with goitrous hypo-thyroidism. Most patients with thyroid autoimmune disease have thyroglobulin antibody. With immunometric assays (sandwich assays), TgAb interference typically produces inappropriately low Tg results, most likely caused by endogenous Tg immune complexes that block one or more of the reagent antibodies from binding endogenous Tg.
Dietary supplements containing biotin may interfere in assays and may
skew analyte results to be either falsely high or falsely low.
For patients receiving the recommended daily doses of biotin, draw
samples at least 8 hours followin the last biotin supplementation.
For patients on mega-doses of biotin supplements, draw samples at
least 72 hours following the last biotin supplementation.
Reported (Analytical Time)
The CPT codes provided are based on AMA guidelines and are for informational purposes only.
CPT coding is the sole responsibility of the billing party.
Please direct any questions regarding coding to the payer being billed.
Reject Criteria: Gross hemolysis; grossly lipemic Transport Temperature: Room temperature