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36297: Adalimumab Level And Anti-drug Antibody for Rheumatic Diseases Print View
Adalimumab Level, Rheum ELISA    mcg/mL 
Adalimumab ADA, Rheum ELISA    AU 
Interpretation      
Comment      

PRIMARY
1 Serum Red Top 2 (1) mL   Room Temperature - 48 Hour(s)/Refrigerated - 7 Day(s)/Frozen - 14 Day(s)  
ALTERNATE

When treatment of rheumatic diseases with adalimumab fails, a physician may need to consider treatment options, such as adjusting dose or dosing intervals, switching to a different TNF blocker, or switching to a non-TNF blocker. This test (1) measures adalimumab drug levels to help differentiate pharmacodynamic or pharmacokinetic conditions to guide therapy, and (2) tests for anti-drug antibodies to help determine if changing the treatment plan is appropriate. Several studies suggest a target adalimumab trough concentration of 5-12 mcg/mL.

The blood should be drawn just before the next infusion of
adalimumab to measure the trough drug level.

Patient Preparation: No biotin supplements 48 hours prior to blood
draw.
Setup Schedule
Tuesday

Reported (Analytical Time)
2 days

CPT Codes
80299,83520

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
**This test is not available for New York patient testing**
Reject Criteria: Serum Separator Tube; gross hemolysis
Transport Temperature: Refrigerated
Specimen Stability:
Frozen (-20 degrees Celsius): 14 days
Frozen (-70 degrees Celsius): 60 days
Methodology: Enzyme Linked Immunosorbent Assay






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