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36311: Infliximab Level And Anti-drug Antibody For Ibd Print View
Infliximab Level, IBD ELISA    mcg/mL 
Infliximab ADA, IBD ELISA    AU 
Interpretation      
Comment      

PRIMARY
1 Serum Red Top 2 (1) mL   Frozen - 14 Day(s)/Refrigerated - 7 Day(s)/Room Temperature - 48 Hour(s)  
ALTERNATE

When treatment of inflammatory bowel disease with infliximab fails, a physician may need to consider treatment options, such as adjusting dose or dosing intervals, switching to a different TNF blocker, or switching to a non-TNF blocker. This test (1) measures infliximab levels to help differentiate pharmacodynamic or pharmacokinetic conditions to guide therapy, and (2) tests for anti-drug antibodies to help determine if changing the treatment plan is appropriate. The American Gastroenterological Association recommends optimal infliximab trough concentration of 5 mcg/mL or greater in patients with active IBD. Data from separate clinical studies suggest an optimal infliximab trough concentration of greater than 3.8 or 6-10 mcg/mL.

The blood should be drawn just before the next
infusion of infliximab to measure the trough drug level

Patient Preparation: For up to 48 hours before blood draw, do not take
multivitamins or dietary supplements containing biotin or vitamin B7.
Setup Schedule
Tuesday

Reported (Analytical Time)
2 days

CPT Codes
80299,83520

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
**This test is not available for New York patient testing**
Reject Criteria: Serum Separator Tube; gross hemolysis; grossly icteric
Transport Temperature: Refrigerated
Specimen Stability:
Frozen (-20 degrees Celsius): 14 days
Frozen (-70 degrees Celsius): 60 days
Methodology: Enzyme Linked Immunosorbent Assay






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