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39481: Cholinesterase, Serum, Plasma, RBC Print View
Cholinesterase RBC S  9572 - 15031  IU/L 
Cholinesterase Plasma KS  Male: 3334 - 7031
Female: 2504 - 6297 
IU/L 
Cholinesterase, Serum S  Male: 3342 - 7586
Female: 2673 - 6592 
IU/L 

PRIMARY
1 Whole Blood EDTA 5 (4) mL   Room Temperature - 24 Hour(s)/Refrigerated - 7 Day(s)  
2 Plasma EDTA 1 (0.5) mL   Refrigerated - 7 Day(s)/Room Temperature - 24 Hour(s)  
3 Serum 1 (0.5) mL   Room Temperature - 24 Hour(s)/Refrigerated - 7 Day(s)  
ALTERNATE

True Cholinesterase (RBC and plasma) activity is decreased in individuals with exposure to organophosphorous insecticides. True Cholinesterase, found in erythrocytes and nerve tissue, is responsible for inactivating acetylcholinesterase at nerve endings. With decreased enzyme activity, patients may display a range of nervous system dysfunction. Analysis of RBC and serum or plasma activity is useful in monitoring exposure and recovery.

Plasma (lavender top, EDTA), Whole Blood
(lavender top, EDTA), Serum (red top, no gel)
5.0 mL whole blood;1.0 mL Plasma; 1.0 mL Serum,
minimum 4.0 mL whole blood; 0.5 mL Plasma; 0.5 mL Serum.
Draw two lavender (EDTA) tubes of whole blood and
one serum red top or SST tube. Spin serum red top
or SST and pour serum into plastic aliquot tube.
Spin one of the lavender tubes and pour plasma into
plastic aliquot tube (Label this vial as Plasma). Send
one refrigerated uncentrifuged whole blood and 1
refrigerated plasma and 1 refrigerated serum.

Do not send packed cells. Do not send only one tube
of whole blood. Plasma cholinesterase results, as
well as the calculated RBC cholinesterase results,
are not accurate if plasma sample is not separated
from the RBC's in a timely manner. Hemolyzed
plasma samples are not acceptable. Hemolysis can
lead to apparent increases in plasma cholinesterase
activity, and could mask an enzyme deficiency.

Rejection Criteria: Hemolyzed or lipemic specimens are not acceptable.
Transport Temperature: Refrigerated
Setup Schedule
Tuesday, Thursday, Saturday

Reported (Analytical Time)
Same day

CPT Codes
82480x2, 82482

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.






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