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39527: Homovanillic Acid, 24-hour Urine Print View
Total Volume     mL 
Homovanillic Acid, 24h U     mg/24 h 
Creatinine, 24-Hour Urine     g/24 h 

PRIMARY
1 Urine with HCL 24 hour 10 (5) mL   Room Temperature - 10 Day(s)/Refrigerated - 14 Day(s)/Frozen - 3 Month(s)  
ALTERNATE

Homovanillic acid (HVA, 4-hydroxy-3-methoxyphenylacetic acid) has been identified as the principal urinary metabolite of dopa and dopamine. HVA is excreted in free form in relatively large amounts, and is frequently measured to support a diagnosis of neuroblastoma and malignant pheochromocytoma. HVA has been used to monitor chronic lead exposure and response to medication, during the treatment of Parkinson's disease.

10 mL urine: pH adjusted to <3.0 using 6N HCl.
Urine without preservative is acceptable if pH is below 6 and the
sample is shipped frozen.

Patient Preparation
It is preferable for the patient to be off medications for three days
prior to collection. However, common antihypertensives (diuretics,
ACE inhibitors, calcium channel blockers, alpha and beta blockers)
cause minimal or no interference. Patient should avoid alcohol,
coffee, tea, tobacco and strenuous exercise prior to collection.
Setup Schedule
Tuesday, Friday

Reported (Analytical Time)
3 days

CPT Codes
83150,82570

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: pH >3.0 and received unfrozen
Transport Temperature:
Preserved urine: Room temperature
Unpreserved urine: Frozen

Methodology: High Performance Liquid Chromatography, Electrochemical Detection






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