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40037: CD21, IHC with Interpretation Print View
Paraffin Block Number:   52 - 380   
Primary Tumor Site:   3.6 - 38   
Quest Internal Number:   Male: 8 - 55
Female: 4 - 35 
 
CD21, IHC w/ interp IHC  < 31 days: 131 - 710
< 24 months: 143 - 439
< 19 years: 152 - 547
>= 19 years: 177 - 583 
 

PRIMARY
1 Tissue Paraffin Block   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  
ALTERNATE
  Slides (5-Unstained)   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  
  Fixed Tissue   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  

CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth- promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in as subset of T cell acute lymphocytic leukemias, but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and centrocytic lymphomas, mature leukemias and lymphomas and at high density in follicular dendretic cells.

Tumor paraffin block (formalin-fixed only) or five 4-micron unstained
sections on Poly-L-Lysine or Silane coated slides. See Specimen
Collection Section, Oncology. Ship at room temperature.
Do not place paper labels with adhesive backing on slides.
Use pencil or xylene resistant pen to write on the frosted end
of the slide only.
Pathology report is required.

Transport Temperature: Room temperature
Setup Schedule
Monday-Saturday

Reported (Analytical Time)
Next day

CPT Code
88342

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: Tissue in formalin






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