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4190: Nicotine and Cotinine, LC/MS/MS, Serum/Plasma Print View
Nicotine LC-MS-MS    ng/mL 
Cotinine LC-MS-MS    ng/mL 

PRIMARY
1 Serum 1 (0.5) mL   Frozen - 30 Day(s)/Refrigerated - 21 Day(s)/Room Temperature - 72 Hour(s)  
ALTERNATE
  Plasma EDTA 1 (0.5) mL   Frozen - 30 Day(s)/Refrigerated - 21 Day(s)/Room Temperature - 72 Hour(s)  
  Plasma EDTA Trace Metal 1 (0.5) mL   Frozen - 30 Day(s)/Refrigerated - 21 Day(s)/Room Temperature - 72 Hour(s)  
  Whole Blood EDTA 7 (2) mL   Refrigerated - 21 Day(s)/Room Temperature - 72 Hour(s)  

This assay is used for the detection of nicotine and cotinine in serum and plasma to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.

Serum collected in red-top tube (no gel).

Transport Temperature: Refrigerated
Setup Schedule
Monday, Wednesday, Friday

Reported (Analytical Time)
4 days

CPT Code
80323

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Rejection Criteria: Serum separator tubes; grossly hemolyzed samples






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