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4191: Leflunomide Metabolite Print View
Teriflunomide LC/MS/MS    ng/mL 

PRIMARY
1 Serum 1 (0.5) mL   Refrigerated - 14 Day(s)/Room Temperature - 5 Day(s)/Frozen - 30 Day(s)  
ALTERNATE
  Plasma Heparinized 1 (0.5) mL   Refrigerated - 14 Day(s)/Frozen - 30 Day(s)/Room Temperature - 5 Day(s)  

Leflunomide is an immunosuppressant medication used in the treatment of rheumatoid arthritis. Leflunomide is rapidly and extensively metabolized to teriflunomide, which is the active form of the medication. Steady state plasma concentrations in patients receiving recommended daily dosages: up to 63,000 ng/mL. It is recommended that all women of childbearing potential who discontinue leflunomide and women receiving treatment who wish to become pregnant undergo the cholestyramine drug elimination procedure. This procedure includes verification that plasma levels of teriflunomide are less than 20 ng/mL by two separate tests at least 14 days apart.

Collect specimen in plain red top tube. Avoid separator tubes. Ship
at room temperature.
Setup Schedule
Tuesday, Thursday, Saturday

Reported (Analytical Time)
Next day

CPT Code
80299

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.






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