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423: Amitriptyline Print View
Amitriptyline LC-MS-MS    mcg/L 
Nortriptyline LC-MS-MS    mcg/L 
Total CALC  100 - 250  mcg/L 

PRIMARY
1 Serum 3 (1.5) mL   Room Temperature - 5 Day(s)/Refrigerated - 7 Day(s)  
ALTERNATE
  Plasma Heparinized 3 (1.5) mL   Room Temperature - 5 Day(s)/Refrigerated - 7 Day(s)  
  Plasma EDTA 3 (1.5) mL   Refrigerated - 7 Day(s)/Room Temperature - 5 Day(s)  
  Plasma Lithium 3 (1.5) mL   Refrigerated - 7 Day(s)/Room Temperature - 5 Day(s)  

The tricyclics are used to treat depression. Nortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and avoid toxicity.

Collect at steady-state trough concentration. Specimen should be
collected >12 hrs after dose. Do not use gel barrier/serum
separator tubes. Sodium or Lithium heparin tubes are acceptable.
Setup Schedule
Tuesday-Saturday

Reported (Analytical Time)
Next day


Notes
Reject Criteria: Gross Hemolysis, Gel Barrier/Serum Separator tubes






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