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4900P: Amikacin, Peak & Trough Print View
Amikacin Peak IMMUNOASSAY  20 - 30  mg/L 
Amikacin Trough IMMUNOASSAY  4 - 8  mg/L 

PRIMARY
1 Serum Peak 1 (0.2) mL   Frozen - 7 Day(s)/Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)  
2 Serum Trough 1 (0.2) mL   Refrigerated - 7 Day(s)/Frozen - 7 Day(s)/Room Temperature - 7 Day(s)  
ALTERNATE
  Plasma EDTA Peak 1 (0.2) mL   Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)/Frozen - 7 Day(s)  
  Plasma Fluo/Oxalat. Peak 1 (0.2) mL   Refrigerated - 7 Day(s)/Frozen - 7 Day(s)/Room Temperature - 7 Day(s)  
  Plasma EDTA Trough 1 (0.2) mL   Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)/Frozen - 7 Day(s)  
  Plasma Fluo/Oxal. Trough 1 (0.2) mL   Room Temperature - 7 Day(s)/Refrigerated - 7 Day(s)/Frozen - 7 Day(s)  

Amikacin is an aminoglycoside which is a polycationic agent that kills aerobic gram-negative bacteria. Aminoglycosides act by binding to the 30S ribosomal subunit of bacterial mRNA, thereby inhibiting protein synthesis. The goal of antimicrobial therapy is to achieve a concentration in plasma such that the bacteria are killed but the host remains undamaged. Both peak and trough specimens are required to monitor toxicity. Renal tubular necrosis and degeneration of the auditory nerve are the side effects most frequently experienced after exposure to high concentrations of the drug.

Trough: Collect just before the next scheduled dose.

Peak: Collect peak at end of 60 minute IV infusion or 30 minutes
after end of 30 minute IV infusion or 60 minutes after IM dose.

Red top tube (plain)
Setup Schedule
Monday-Saturday

Reported (Analytical Time)
Same day

CPT Code
80150x2

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
When using this test code, both Peak and Trough specimens must be sent together. Collection Container: Red top tube (plain) Rejection Criteria: Do not collect in Gel Barrier/Serum Separator Tube or tubes containing Heparin anticoagulant.






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