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4944: Beta-2-microglobulin, Random Urine Print View
B2 Microglobulin, Urine NEPH  < .24  mg/L 

PRIMARY
1 Urine 1 (0.5) mL   Room Temperature - 8 Hour(s)/Refrigerated - 7 Day(s)/Frozen - 12 Month(s)  
ALTERNATE

Beta-2 Microglobulin (B2M) is a low molecular weight protein that forms the light chain component of the histocompatibility antigen. It is synthesized by all nucleated cell types. It is an integral part of the class I MHC antigens and is present in all body fluids. B2M is filtered through the glomeruli of the kidney and is then reabsorbed and catabolised by the proximal tubular cells. In normal patients only trace amounts of B2M appear in the urine. Elevated urine B2M is seen in tubulo-interstitial disorders. Increased urine B2M is seen in cadmium exposure, diatrizoate, exercise, fever, nephrectomy, semen. There is evidence that monitoring B2M levels in HIV-infected individuals offers an idependent predictor of progression to AIDS, leukemia and lymphoma.

Patient should void bladder, then drink at least 500 mL of water. A
urine sample should be collected within 1 hour and pH adjusted to pH
6-8 with 1M NaOH. Beta-2-Microglobulin is unstable in acidic urine
(less than pH 6).

Transport Temperature: Frozen

Reject Criteria: Received room temperature
Setup Schedule
Tuesday-Saturday

Reported (Analytical Time)
Same day

CPT Code
82232

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.






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