Patients with a chronic form of urticaria who are positive with the functional Histamine Release (Chronic Urticaria) test have an autoimmune basis for their disease. A positive result does not indicate which autoantibody (anti-IgE or anti-Fc epsilon RI alpha chain) is present. A positive anti-IgE antibody does not exclude the presence of anti-Fc epsilon RI alpha chain antibody. Autoimmune thyroid disease coexists in approximately 25% of autoimmune chronic urticaria patients.
Serum should be separated from the cells as soon as possible
after visible clot formation (usually 15-30 minutes after
Patient Preparation: Overnight fasting is preferred. Patients
taking calcineurin inhibitors should stop their medication
for 72 hours prior to draw.
Specimen collection after fluorescein dye angiography should be
delayed for at least 3 days. For patients on hemodialysis, specimen
collection should be delayed for 2 weeks. According to the assay
manufacturer Siemens: "Samples containing fluorescein can produce
falsely depressed values when tested with the ADVIA Centaur TSH3
Reported (Analytical Time)
The CPT codes provided are based on AMA guidelines and are for informational purposes only.
CPT coding is the sole responsibility of the billing party.
Please direct any questions regarding coding to the payer being billed.
Preferred Specimen: 6 mL (3.0 mL minimum) serum collected in red-top (no gel) Set-up Schedule: See individual assays Set-up Schedule: See individual assays Reference Range: See individual assays Methodology: See individual assays Reject Criteria: Gross hemolysis; lipemic specimen; icteric specimen; SST(R) tubes; sample other than serum; heavy visible particulate matter; moderate hemolysis Transport Temperature: Room temperature