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90363: B-cell Receptor IGK Gene Rearrangement, PCR Print View
Clinical Indication:      
Specimen Source:      
Block/Specimen ID:      
IGK Result      
Pathologist Interpretation      

PRIMARY
1 Whole Blood EDTA 5 (3) mL   Room Temperature - 7 Day(s)/Refrigerated - 7 Day(s)  
ALTERNATE
  Tissue Paraffin Block   Room Temperature - 12 Month(s)  
  Bone Marrow EDTA   Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)  
  Needle washings   Room Temperature - 7 Day(s)/Refrigerated - 7 Day(s)  
  Tissue   Frozen - 12 Month(s)  
  Slides (12-Unstained)   Room Temperature - 12 Month(s)  

This assay, which interrogates the immunoglobulin kappa light chain gene (IGK) by a PCR method based on the BIOMED-2 consensus, is useful for establishing clonality of B-cell lymphoid neoplasms and in the identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a B-cell neoplasm. It can be used in association with the immunoglobulin heavy chain (IGH PCR assay test code 90362), since false-negative results can occur in up to 10-15% of B-cell malignancies when testing IGK only.

Collect whole blood or bone marrow in and EDTA (lavender-top) tube and
ship refrigerated or room temperature. Stability of whole blood and
bone marrow samples at room and refrigerated temperatures is 1 week.

Paraffin blocks are to be shipped at room temperature. Stability for
paraffin block is indefinite.

For tissue samples, fresh frozen tissue is preferred and to be shipped
frozen. Frozen tissue is stable for approximately 1 year at -70 C.

Needle washings in alcohol based fixative (eg. CytoLyt) are
acceptable. Please include pathology report for all fresh FNA, frozen
tissue and FFPE cases (partial/preliminary reports OK).
Setup Schedule
Monday, Wednesday

Reported (Analytical Time)
5 days

CPT Codes
81264,G0452+26

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Transport Temperature: Room temperature. Methodology: Polymerase Chain Reaction, Fragment Analysis **Please note: Test includes pathologist interpretation**






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