abcdefghijklmn
opqrstuvwxyz
Test Menu
Test Change Details
Allergy & Immunology
Cardiology & Coagulation
Dermatopathology
Endocrinology
Gastroenterology
Genetics
Hepatology
Infectious Disease
Microbiology
Nephrology
Neurology
Oncology
Pathology
Pediatrics
Rheumatology
Toxicology
Urology
Women's Health
90469: Thyroid Cancer Mutation Panel (BRAF, RAS, RET/PTC, PAX8/PPAR) Print View
Specimen Source      
Block/Specimen ID      
BRAF Mutation PCR  Not detected   
HRAS Mutation PCR  Not detected   
KRAS Mutation PCR  Not detected   
NRAS Mutation PCR  Not detected   
RETPTC1 PCR  Not detected   
RETPTC3 PCR  Not detected   
PAX8/PPAR gamma PCR  Not detected   

PRIMARY
1 Slides (Unstained) 4 (2) mL   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  
ALTERNATE
  Tissue Paraffin Block   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  
  Needle washings   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  

The thyroid mutation panel assesses for all 8 of the most common mutations or rearrangements associated with thyroid neoplasia. The BRAF codon 600 mutation, and RET/PTC1 and RET/PTC3 rearrangements are highly associated with papillary thyroid cancer, the PAX8-PPAR{gamma} with follicular carcinomas and Ras mutations (in either HRAS, KRAS and NRAS) usually with follicular neoplasms. See test codes 90477 (BRAF), 90473(RET-PTC), 90474 (PPAR{gamma}), and 90479 (Ras panel) for individual components. A thyroid cytology diagnosis code with reflex to molecular, as appropriate, is also available.

Needle washings in alcohol based fixative (e.g. cytolyt), 4 slides,
or Formalin fixed, paraffin embedded tissue block FNA or FFPE
specimens are acceptable for the assay. All specimens must be
accompanied with Pathology report. Specimens will be examined by a
pathologist for confirmation and microdissection if warranted.
A minimum of 4 FNA slides should be submitted and three should be
without coverslips. Coverslipped slides will delay reporting of
results.


Transport Temperature: Ship room temperature

Rejection Criteria: Sample received frozen; Baked slides
Setup Schedule
Sunday-Saturday

Reported (Analytical Time)
5 days

CPT Code
81210

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
*Includes: BRAF Mutation Analysis, Papillary Thyroid Cancer *RAS Mutation Analysis, Thyroid Cancer *RET/PTC Rearrangement, Thyroid Cancer *PAX8/PPAR[gamma] Translocation, Thyroid Cancer






1996 - 2017 Quest Diagnostics Nichols Institute of Valencia
For test information, please call Client Services at 800-421-4449.

San Francisco Web Design & Database