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90473: RET/PTC Rearrangement, Thyroid Cancer Print View
Specimen Source      
Block/Specimen ID      
RETPTC1 RT-PCR  Not detected   
RETPTC3 RT-PCR  Not detected   

PRIMARY
1 Slides (Unstained) 4 (4) mL   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  
ALTERNATE
  Tissue Paraffin Block   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  

RET/PTC gene fusion is detected in 5-40% of papillary thyroid carcinomas, but has been reported at low frequency in other types of thyroid lesions. Correlation with morphologic and clinical findings is thus required. The assay tests for both RET/PTC1 and RET/PTC3 rearrangements using a reverse transcription PCR assay. The lower limit of sensitivity is approximately 2.5% mutation-bearing cells in a mixed sample, but can very due to RNA preservation.

Needle washings in alcohol based fixative (e.g. cytolyt), 4 slides or
Formalin fixed, paraffin embedded tissue block FNA or FFPE specimens
are acceptable for the assay. All specimens must be accompanied with
Pathology report. Specimens will be examined by a pathologist for
confirmation and microdissection if warranted. A minimum of 4 FNA
slides should be submitted and three should be without coverslips.
Coverslipped slides will delay reporting of results.


Transport Temperature: Ship room temperature
Setup Schedule
Tuesday, Thursday

Reported (Analytical Time)
3 days

CPT Code
81479

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Specimen Stability: Room temperature and Refrigerated: Indefinite Frozen: Do not Freeze






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