Thyroid FNA Cytomorphology with Molecular Reflex - Quest Diagnostics Nichols Institute of Valencia

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90818: Thyroid FNA Cytomorphology with Molecular Reflex

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	Specimen Source:
	Block/Specimen ID:
	Clinical Indication:
	Ultrasound Findings
	Collection Date
	Thyroid,FNA rfl Molecular


PRIMARY
1	Needle washings	Room Temperature - 8 Day(s)/Refrigerated - 8 Day(s)
2	Slides (4-Unstained)	Room Temperature - 8 Day(s)/Refrigerated - 8 Day(s)
ALTERNATE

Both benign and maligant thyroid neoplasms are associated with specific molecular alterations that can aid in diagnosis. Among thyroid tumors, BRAF V600E mutation (40-50% of cases) and RET over expression through juxtaposition to the PTC1 or PTC3 genes by chromosome fusion (5-40% of cases) are associated specifically with papillary thyroid cancer (PTC). Follicular thyroid carcinoma is specifically associated with PPARG-PAX8 gene fusions in thyroid cancer but appear less specifically associated with morphologiv findings.

Express a small portion of the FNA from needle directly onto glass
slide; and air dry or fix immediately by immersing in alcohol or by
fixing with a commercially prepared cytology spray fixative. Label
each slide with patient name, pathology sample ID and the number of
needle pass (i.e. 1 for 1st, 2 for 2nd, etc). The needle should then
be washed in a screw top vial of alcohol-based fixative (e.g. CytoLyt)
and labled with patient name, pathology sample ID and FNA location.
FNAs from different locations (e.g. distinct nodules) should be
collected individually on different slides and needle washings (e.g.
A-left lobe, B-right lobe).

Setup Schedule

Monday-Friday

Reported (Analytical Time)

7 days

CPT Code

88173

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes

Methodology: Cytomorphology Review and Polymerase Chain Reaction-based Molecular Testing.

Transport Temperature: Room temperature

Reject Criteria: Broken slides beyond repair; unlabled container or slide; leakage of fluid during transport; mismatch between name of patient on slide and requisition.

Additional Information: If cytomorphology results belong to an indeterminate group it will be reflexed to molecular testing at an additional charge.

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