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90923: Fibrinolysis Comprehensive Panel Print View
Interpretation      
Alpha 2-Antiplasmin CHROM  85 - 156  % 
D-Dimer IMMUNOTURBID  < .50  mcg/mL FEU 
Euglobulin Clot Lysis Time CLOT DISSOL.  > 60  min 
FDP-Latex LATEX AGGL  < 5  mcg/mL 
PAI-1 Antigen EIA  4 - 43  ng/mL 
Plasminogen Activity CHROM SUBS  65 - 176  % 
TPA, EIA EIA  < 12.9  ng/mL 
Fibrin Monomer HA  Negative   

PRIMARY
1 Plasma Citrated 1 (0.8) mL   Frozen - 14 Day(s)  
ALTERNATE

An increase in PAI-1 antigen is associated with an increased risk for post-operative venous thrombosis, myocardial infarction, and (probably) stroke. A severe deficiency of alpha-2 antiplasmin or PAI-1 antigen has been associated with bleeding. A shortened euglobulin lysis time correlates with a severe deficiency of alpha-2 antiplasmin or PAI-1 antigen. Elevations in fibrin monomer, fibrinogen degradation products, and D-dimer usually indicate vascular thrombosis (mainly venous) but are also associated with malignancy and infection. Conversely, a normal D-dimer and/or negative fibrin monomer suggests the absence of deep venous thrombosis and pulmonary emboli. Marked reduction in plasminogen has been associated with a prothrombotic state, and an elevated TPA level is a risk marker of coronary artery disease.

Specimen: Plasma 3.2% Sodium Citrate (lt. blue-top) [X4]
1 mL [x4] - Minimum: 0.8 mL [x4]

Platelet Poor Plasma: Centrifuge light blue-top tube 15 minutes at
approx. 1500 g within 60 minutes of collection. Using a plastic
pipette, remove plasma, taking care to avoid the WBC/platelet buffy
layer and place into a plastic vial. Centrifuge a second time and
transfer platelet-poor plasma into a new plastic vial. Plasma must be
free of platelets (<10,000/mcl). Freeze immediately and ship on dry
ice. Avoid hemolysis. Avoid lipemia.
Setup Schedule
Monday-Saturday

Reported (Analytical Time)
9 days

CPT Codes
85410,85379,85360,85362x2,85415x2,85420

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
REJECT CRITERIA: Hemolysis, Lipemia, Contaminated plasma, Improperly stored or handled specimens, Received room temperature, Received refrigerated. Patient Preparation: Morning fasting is required Includes: Alpha 2-Antiplasmin; D-Dimer, Quantitative; Euglobulin Clot Lysis Time; Fibrinogen Degradation Products (FDP); Plasminogen Activator Inhibitor (PAI-1) Antigen; Plasminogen Activity; Tissue Plasminogen Activator (TPA), EIA; Fibrin Monomer METHODOLOGY: Chromogenic Assay, Enzyme Immunoassay, Clot Dissolution, Latex Agglutination, Hemagglutination






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