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90924: Hepatitis C Viral RNA Genotype 1 NS3 Drug Resistance Print View
HCV NS3 Subtype PCR     
Grazoprevir Resistance      
Paritaprevir Resistance      
Simeprevir Resistance      

PRIMARY
1 Plasma EDTA 2 (0.6) mL   Refrigerated - 14 Day(s)/Frozen - 42 Day(s)/Room Temperature - 72 Hour(s)  
ALTERNATE
  Serum 2 (0.6) mL   Refrigerated - 14 Day(s)/Frozen - 42 Day(s)/Room Temperature - 72 Hour(s)  
  PPT Potassium EDTA(white)   Room Temperature - 72 Hour(s)/Refrigerated - 14 Day(s)/Frozen - 42 Day(s)  

This assay may be used to detect grazoprevir, simeprevir and paritaprevir resistance-associated NS3 mutations in genotype 1 NS3 protease inhibitor treatment-experienced patients and also the Q80K polymorphism in patients being considered for a simeprevir-containing regimen.

Separate serum or plasma from whole blood within 24 hours of
collection by centrifugation at 800-1600 x g for 20 minutes at room
temperature. Transfer the plasma to a properly identified, sterile,
polyproprylene screw-cap vial and ship refrigerated or frozen.
Please note that an HCV genotype 1 is required for this test.
Setup Schedule
Monday

Reported (Analytical Time)
4 days

CPT Code
87902

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: Specimens using heparin as the anticoagulant; gross lipemia; gross hemolysis. Transport Temperature: Refrigerated Methodology: Polymerase Chain Reaction and Sequencing






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