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91027: Cervical Cancer, TERC, FISH Print View
Cervical Cancer, TERC, FISH FISH     
Specimen Type/Source/Vol:      
Clinical Indication:      
LSIL/HSIL on prev PAP/Bx      
HX on HPV      
Client Accession #:      
Patient ID:      
Referring Physician:      
Referring Physician Phone:      
Client/Phone #:      

PRIMARY
1 ThinPrep Vial 15 (3) mL   Refrigerated - 30 Day(s)/Room Temperature - 30 Day(s)  
ALTERNATE
  SurePath Vial   Refrigerated - 30 Day(s)/Room Temperature - 30 Day(s)  

This FISH assay detects increases in the copy number of the telomerase component gene TERC in cervical cytology specimens, which is a finding common in high-grade squamous intraepithelial neoplasia (HSIL) and invasive carcinoma. A positive result in this assay is presence of extra copies of the TERC gene by either locus- specific 3q26 amplification or polysomy of chromosome 3. This is associated with HSIL and a subset of ASC-H which may require more intensive follow-up. Uses of this assay include: 1. Assist in separating HSIL from ASC-H detected on Pap smear; 2. Assist in separating HSIL from LSIL detected on Pap Smear; 3. Further evaluation of atypical Pap findings when high risk HPV is negative.

Cytopathology report must accompany test order.

Will attempt on any specimen; Do Not Reject.
Setup Schedule
Monday-Saturday

Reported (Analytical Time)
Same day

CPT Codes
88275x2,88271x2

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Fluorescence in situ Hybridization (FISH) If results are not possible due to insufficient cells for analysis, this test will be canceled and replaced with Cervical Cancer, TERC, FISH Insufficient Specimen, at no charge.






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