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91115: Dabigatran with Reflex to Thrombin Time Print View
Interpretation      
Dabigatran   64 - 443  ng/mL 

PRIMARY
1 Plasma Citrated 1 (0.5) mL   Frozen - 30 Day(s)  
ALTERNATE

Dabigatran is a new oral direct anti-thrombin drug and an alternative to Warfarin. The drug received FDA clearance in 2010 for the indication of stroke prevention in patients with atrial fibrillation. Routinely, the drug does not need to be monitored, however, there are instances where monitoring is needed: (1) Detetmining of failure of therapy vs. poor compliance (2) Potential dose adjustment required for renal or hepatic dysfunction (3) Titration.

Whole blood collected in 3.2% sodium citrate (light blue-top tube).
Collect 90 to 120 minutes after the last dose (preferably after at
least 3 doses). Centrifuge (light blue-top) tube 15 minutes at
approximately 1500g within 60 minutes of collection.
Using a plastic pipette, remove plasma, taking care to avoid the
WBC/platelet buffy layer and place into a plastic vial. Centrifuge a
second time and transfer platelet-poor plasma into a new plastic vial.
Plasma must be free of platelets (<10,000/mcL).
Freeze immediately and ship on dry ice.
Setup Schedule
Tuesday, Thursday, Saturday

Reported (Analytical Time)
Same day

CPT Code
80299

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Clotting Assay Transport Temperature: Frozen Reject Criteria: Gross hemolysis; visible fibrin clot; received room temperature or refrigerated Additional Information: If the Dabigatran result is <45 ng/mL, then Thrombin Time will be performed at an additional charge (CPT code: 85670).






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