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91216: Lung Cancer Mutation Panel (EGFR, KRAS, ALK) Print View
Specimen Source:      
Specimen/Block Number:      
EGFR Mutation      
KRAS Mutation      
Lung Ca (NSCLC),ALK,FISH      
Specimen Type/Source/Vol:      
Clinical Indication:      
Referring Physician:      
Referring Physician Phone:      
Client/Phone #:      
Client Accession #:      
Patient ID:      

PRIMARY
1 Tissue Paraffin Block 1 (1) g   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  
ALTERNATE

This panel is comprised of mutational analysis of the EGFR and KRAS genes and assessment for ALK locus rearrangement using an FDA-cleared FISH assay. These are the most common tumor-associated genetic changes that have been shown to have prognostic and therapeutic consequences in non-small cell lung cancer (NSCLC) and help guide therapy. Patients with EGFR mutations are generally responsive to EGFR-directed kinase inhibitors, whereas those with evidence of ALK gene rearrangements are candidates for treatment with the ALK inhibitor crizotinib. The presence of KRAS mutation in lung adenocarcinoma predicts for non-response to kinase inhibitors and for tumors with inferior outcome.
Setup Schedule
Monday-Friday

Reported (Analytical Time)
7 days

CPT Codes
81235,81276,81275,88274,88271x2

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Transportation Temperature: Room temperature Specimen Stability: Room temperature and Refrigerated: Indefinite Frozen: Unacceptable






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