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91290: Th/to Antibody [233] Print View
Th/To Antibody IPP  Negative   

PRIMARY
1 Serum 1 (0.5) mL   Refrigerated - 14 Day(s)/Room Temperature - 7 Day(s)/Frozen - 60 Day(s)  
ALTERNATE
  Plasma EDTA 1 (0.5) mL   Refrigerated - 14 Day(s)/Frozen - 60 Day(s)/Room Temperature - 7 Day(s)  

The Th/To is a component of the 7-2/MRP RNP. Most of the 7-2/MRP RNP is found in the GC region of the nucleolus and <1% of this snoRNP appears located in mitochondria. The Th/To antibodies are present in 10-19% of patients with limited SSc, in 11% of patients with diffuse cutaneous SSc, and in 3% of patients with primary Raynaud's disease. Anti-Th/To antibody has been shown to be highly specific for patients with SSc. The anti-Th/To antibody detection is an in-house bioassay performed at RDL for qualitative determination of Th/To antibody in serum by immunoprecipitation. The Th/To antibody assay will be labeled as an "Analytic Specific Reagent (ASR)".
Setup Schedule
Monday-Thursday

Reported (Analytical Time)
10 days

CPT Code
83516

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Transport Temperature: Refrigerated






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