A minimal four-fold increase between pre-immunization and post-immunization sera is considered a normal response to tetanus toxoid. Levels greater than or equal to 0.10 IU/mL are considered protective.
Draw pre-immunization sample in a red-top Vacutainer.
After clotting, centrifuge and draw off the serum. Label with
patient identification, date drawn, and the word PRE. Store
frozen until the sample is submitted, after the post-immunization
sample is drawn.
Draw post-immunization sample 2-3 weeks after vaccination and
prepare as described above. Label the sample with patient
identification, date drawn, and the word POST. Dates drawn
must be different.
Submit both the PRE and POST samples together. UNDER NO
CIRCUMSTANCES should these samples be mixed.
Tuesday, Thursday, Saturday
Reported (Analytical Time)
The CPT codes provided are based on AMA guidelines and are for informational purposes only.
CPT coding is the sole responsibility of the billing party.
Please direct any questions regarding coding to the payer being billed.
Specimen Requirements: 1mL (0.3 mL minimum) serum collected in each of two separate tubes. Transport Temperature: Room temperature Reject Criteria: Gross hemolysis; gross lipemia; gross icteric; PRE and POST samples must be received; samples must be dated; sample must be labeled PRE and POST