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91445: T-cell Clonality Panel (TCRB, TCRG), PCR Print View
Clinical Indication:      
Specimen Source:      
Block/Specimen ID:      
TCRG Result      
TCRB Result      
Pathologist Interpretation      

PRIMARY
1 Whole Blood EDTA 5 (3) mL   Room Temperature - 7 Day(s)/Refrigerated - 7 Day(s)  
ALTERNATE
  Tissue   Frozen - 12 Month(s)  
  Needle washings   Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)  
  Slides (12-Unstained)   Room Temperature - 12 Month(s)  
  Tissue Paraffin Block   Room Temperature - 12 Month(s)  
  Bone Marrow EDTA   Refrigerated - 7 Day(s)/Room Temperature - 7 Day(s)  

This test, which interrogates both the T-cell receptor beta (TCRB) locus and the T-cell receptor gamma (TCRG) locus by a PCR method based on the BIOMED-2 consenus, is useful in patients with suspected T-cell malignancies or to evaluate for residual disease after treatment. Several published studies have demostrated that the combination of TCRB and TCRG PCR using the BIOMED-2 method can detect virtually all clonal T-cell populations.

Collect whole blood or bone marrow in an EDTA (lavender-top) tube and
ship refrigerated or room temperature. Stability of whole blood and
bone marrow samples at room and refrigerated temperatures is 1 week.

Paraffin blocks are to be shipped at room temperature. Stability for
paraffin blocks is indefinite.

For tissue samples, fresh frozen tissue is preferred and to be shipped
frozen. Frozen tissue is stable for approximately 1 year at -70 C.

Tissues in formalin fixative or RPMI are to be shipped at room
temperature or refrigerated.

Needle washings in alcohol based fixative (eg. CytoLyt) are
acceptable. Please include pathology report for all fresh FNA, frozen
tissue and FFPE cases (partial/preliminary reports OK).
Setup Schedule
Tuesday, Thursday, Saturday

Reported (Analytical Time)
3 days

CPT Codes
81342,81340,G0452

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Transport Temperature: Room temperature Methodology: Polymerase Chain Reaction, Fragment Analysis **Please note: Test includes pathologist interpretation**






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