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91472: Rheumatoid Arthritis Diagnostic IdentRA® Panel 2 Print View
Rheumatoid Factor TURB  < 14  IU/mL 
CCP Antibody (IgG) ELISA    Units 
14-3-3 eta Protein ELISA  < .2  ng/mL 

PRIMARY
1 Serum 3 (1.5) mL   Room Temperature - 4 Day(s)/Refrigerated - 7 Day(s)/Frozen - 21 Day(s)  
ALTERNATE

Early diagnosis of rheumatoid arthritis (RA),ie, diagnosis before significant joint erosion occurs, is difficult. Psoriatic arthritis can also be difficult to diagnose clinically early in the disease process, and there are no specific biomarkers. The 14-3-3 (eta) protein is an emerging biomarker for RA and erosive psoriatic arthritis diagnosis. It may play a biologic role in the joint erosive process. Blood levels appear to be elevated in patients with RA, but not in other diseases including psoriasis, osteoporosis, gout, ulcerative colitis, type 1 diabetes, systemic lupus erythematosus, Crohn disease, primary Sjogren syndrome, scleroderma, and multiple sclerosis. The 14-3-3 eta protein, used in conjunction with rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) antibody, may improve diagnostic sensitivity in the early diagnosis of RA. It may also help differentiate those with psoriatic arthritis joint damage from those without joint damage.

Allow blood to clot (10-15 minutes) at room temperature.
Centrifuge and separate from cells. Freeze as soon as possible.
Ship frozen.
Setup Schedule
Monday, Wednesday, Friday

Reported (Analytical Time)
3 days

CPT Codes
86431,86200,83520

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Rejection Criteria: Gross hemolysis; Lipemia; plasma; heat-treated samples Transport Temperature: Refrigerated






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