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91606: FISH, High-Grade Lymphoma Panel Print View
FISH, High-Grade Lymphoma FISH     
Specimen Type/Source/Vol:      
Clinical Indication:      
Referring Physician:      
Referring Physician Phone:      
Client/Phone #:      
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PRIMARY
1 Bone Marrow Transport Med 3 (1) mL   Refrigerated - 48 Hour(s)/Room Temperature - 48 Hour(s)  
ALTERNATE
  Tissue TM - Tumor Biopsy   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
  Sod Heparin Lead-Free   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
  Bone Marrow Hep(Royal Bl)   Refrigerated - 48 Hour(s)/Room Temperature - 48 Hour(s)  
  Bone Marrow Hep lead-free   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
  Bone Marrow Heparinized   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
  Whole Blood EDTA 5 (3) mL   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
  Whole Blood Heparin 5 (3) mL   Refrigerated - 48 Hour(s)/Room Temperature - 48 Hour(s)  
  Whole Blood ACD Sol B 5 (3) mL   Refrigerated - 48 Hour(s)/Room Temperature - 48 Hour(s)  
  WB NaHep Trace Metal   Refrigerated - 48 Hour(s)/Room Temperature - 48 Hour(s)  
  Whole Blood ACD Sol A 5 (3) mL   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  

High-grade B-cell lymphoma can be difficult to classify if histologic and immunophenotypic features are not entirely typical. Large B-cell lymphoma with monomorphic appearance or very high mitotic rate and Burkitt lymphoma cases that have atypical immunophenotypic or morphologic appearances present diagnostics difficulties. The FISH panel for MYC (8q24), t(14;18) (IGH-BCL2) and BCL6 (3q27) translocations, provides additional diagnostics information that may help in final classification and therapy selection in high-grade B-cell lymphomas as well as to assess for "double-hit" lymphomas and "triple-hit" lymphomas.

Bone Marrow, 1-3 mL in transport medium (preferred) or sodium
heparin (green-top, dark/royal blue-top or tan-top) tubes are
acceptable containers for this test.
Lymph node/tumor:5x5 mm fresh tumor biopsy in a transport medium.
Paraffin Block: Formalin fixed paraffin embedded tissue.
Transport media available upon request.
Ship at room temperature. Do not Freeze.
SPECIMEN VIABILITY DECREASES DURING TRANSIT. SEND SPECIMEN TO
TESTING LAB FOR VIABILITY DETERMINATION. DO NOT REJECT.
Setup Schedule
Sunday-Saturday

Reported (Analytical Time)
5 days

CPT Codes
88275x3,88271x6

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.






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