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92053: ASCVD Risk Panel with Score Print View
Cholesterol, Total     mg/dL 
HDL Cholesterol     mg/dL 
Triglycerides     mg/dL 
LDL Chol, Calculated     mg/dL 
Cholesterol/HDL Ratio     calc 
Non-HDL Cholesterol   < 20 years: <= 119
>= 20 years: Call Client Services 
mg/dL calc 
10 Year ASCVD Risk     % 
10 Year ASCVD Risk Goal     % 
Lifetime ASCVD Risk     % 
African American      
Systolic Blood Pressure     mmHg 
Treatment for High B.P.      
Diabetes      
Current Smoker      

PRIMARY
1 Serum 2 (1) mL   Frozen - 15 Day(s)/Refrigerated - 7 Day(s)/Room Temperature - 48 Hour(s)  
ALTERNATE
  Plasma Heparinized 1 (0.5) mL   Room Temperature - 48 Hour(s)/Refrigerated - 7 Day(s)/Frozen - 15 Day(s)  
  Plasma Lithium Heparin 1 (0.5) mL   Room Temperature - 48 Hour(s)/Frozen - 15 Day(s)/Refrigerated - 7 Day(s)  

This panel provides the 10-year and lifetime risk of atherosclerotic cardiovascular disease (ASCVD) using lipid results with anthropomophic data and family history. The ASCVD risk assessment is recommended in the 2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atheroscierotic Cardiovascular Risk in Adults.

If a cholesterol measurement is to be performed along with
triglycerides, the patient should be fasting 9-12 hours prior to
collection.

The assay manufacturer, Roche, notes that N-acetylcysteine, when
administered in high concentrations (such as for treatment of
acetaminophen overdose), can interfere with their assay for HDL
cholesterol, leading to falsely low results.

For risk calculations to be performed, the following patient specific
information have to be provided at time or order:
Age: Years
Gender M (for male) or F (for female)
Race - African American: Y (for yes) or N (for no)
Systolic Blood Pressure: mmHg
Treatment for High Blood Pressure: Y (for yes) or N (for no)
Diabetes Status: Y (for yes) or N (for no)
Smoking Status: Y (for yes) or N (for no)

Patient Preparation

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine
(NAC), when administered in therapeutic concentrations (for the
treatment of acetaminophen overdose), has been...determined to
interfere with assays for...Cholesterol, Uric Acid" where "NAC
interference may lead to falsely low results." According to Beckman
Coulter, the NAC interference should be insignificant by 12 hours
after completion of the initial loading dose of an IV infusion
treatment regimen consisting of an initial loading dose of 150 mg/kg
administered over 1 hr, a second dose of 50 mg/kg administered over 4
hrs and a third dose of 100 mg/kg administered over 16 hrs.
Setup Schedule
Monday-Friday

Reported (Analytical Time)
3 days

CPT Codes
82465,83718,84478

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: Gross hemolysis; anticoagulants other than heparin; moderate to gross icterus;

Transport Temperature: Room temperature

Methodology: Spectrophotometry, Enzymatic

If Triglyceride is >400 mg/dL then Cholesterol, Direct LDL will be performed at an additional charge (CPT code(s) 83721).






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