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92497: FISH, Myeloma, 17p-, rea 14q32 with Reflexes Print View
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FISH, Myeloma, Risk Panel FISH     

PRIMARY
1 Bone Marrow Transport Med 3 (1) mL   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
ALTERNATE
  Bone Marrow Heparinized   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)  
  Bone Marrow Hep lead-free   Refrigerated - 48 Hour(s)/Room Temperature - 48 Hour(s)  

Plasma cell myeloma (PCM) is characterized by the proliferation of malignant monoclonal plasma cells in the bone marrow. Initial FISH testing is performed to detect high risk rearrangements of IGH (14q32) and deletion of TP53 (17p13.1). The prognostic panel also includes probes to detect gains of 1q and monosomy or deletion 13q associated with less favorable outcome and gains of chromosome 9, 11, and 15 associated with more favorable outcome.

Submit 1-3 mL bone marrow aspirate in transport media (preferred) or
bone marrow in sodium heparin tubes.

Ship at room temperature. Do not Freeze.

Specimen viability decreases during transit. Send specimen to testing
lab for viability determination. Do not reject.
Setup Schedule
Sunday-Saturday

Reported (Analytical Time)
8 days

CPT Codes
88275x5,88271x11

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Transport Temperature: Room temperature Methodology: Fluorscence In Situ Hybridization (FISH) When the result for IGH rearrangement is positive during initial FISH analysis, the IGH Panel (MAFB, MAF, FGFR3, CCND1) will be performed at an additional charge (CPT code(s): 88271(x8), 88275(x4)). This allows identification of high risk t(j;14), and standard risk t(11;14). Please note that partial reports are issued when sample is insufficient to perform all components of the FISH panel.






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