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Interpretation Summary |
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TP53 Sequencing |
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TP53 Seq Interp |
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TP53 Del/Dup |
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TP53 Del/Dup Interp |
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Comprehensive Interp |
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Additional Information |
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| PRIMARY |
| 1 |
Whole Blood EDTA |
4 (2) mL
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Refrigerated - 8 Day(s)/Room Temperature - 8 Day(s) |
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| ALTERNATE |
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Whole Blood ACD Sol A |
4 (2) mL
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Room Temperature - 8 Day(s)/Refrigerated - 8 Day(s) |
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Mutations in the TP53 gene lead to Li-Fraumeni syndrome (LFS), which is an inherited cancer syndrome with an early onset of tumors, multiple tumors within an individual, and often multiple affected family members. The most common types of tumors are soft tissue sarcomas and osteosarcomas, breast cancer, brain tumors, leukemia, and adrenocortical carcinoma. Sequencing and deletion/duplication analyses of the TP53 gene will identify individuals who are affected with LFS and therefore at risk for TP53-related cancers.
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Whole Blood: Normal phlebotomy procedure; specimen stability is
crucial. Store and ship room temperature immediately. Do not freeze.
Send report of results for family member with known BRCA mutation.
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| Setup Schedule |
| Tuesday, Thursday, Saturday |
| Reported (Analytical Time) |
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12 days
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CPT Codes
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81405,81479
The CPT codes provided are based on AMA guidelines and are for informational purposes only.
CPT coding is the sole responsibility of the billing party.
Please direct any questions regarding coding to the payer being billed.
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| Notes |
| Reject Criteria: Gross hemolysis; clotted specimens Transport Temperature: Room temperature Report available: 12 days from completed pre-authorization Methodology: Exon Capture, Next Generation Sequencing with Microarray confirmation |
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