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93234: Watson Genomics, Quest Diagnostics, Core Print View
Tumor Tissue Type:      
Block ID:      
Diagnosis:      
Source:      
Paired Blood Submitted      
Report Germline Consent      
Overall Interpretation      
Gene Name #1      
Mutation #1      
Alteration Type #1      
Mutation Frequency #1     % Frequency 
Tumor Type Drugs #1      
Non-Tumor Type Drugs #1      
Clinical Trials #1      
Gene Name #2      
Mutation #2      
Alteration Type #2      
Mutation Frequency #2     % Frequency 
Tumor Type Drugs #2      
Non-Tumor Type Drugs #2      
Clinical Trials #2      
Gene Name #3      
Mutation #3      
Alteration Type #3      
Mutation Frequency #3     % Frequency 
Tumor Type Drugs #3      
Non-Tumor Type Drugs #3      
Clinical Trials #3      
Gene Name #4      
Mutation #4      
Alteration Type #4      
Mutation Frequency #4     % Frequency 
Tumor Type Drugs #4      
Non-Tumor Type Drugs #4      
Clinical Trials #4      
Gene Name #5      
Mutation #5      
Alteration Type #5      
Mutation Frequency #5     % Frequency 
Tumor Type Drugs #5      
Non-Tumor Type Drugs #5      
Clinical Trials #5      
Gene Name #6      
Mutation #6      
Alteration Type #6      
Mutation Frequency #6     % Frequency 
Tumor Type Drugs #6      
Non-Tumor Type Drugs #6      
Clinical Trials #6      
Gene Name #7      
Mutation #7      
Alteration Type #7      
Mutation Frequency #7     % Frequency 
Tumor Type Drugs #7      
Non-Tumor Type Drugs #7      
Clinical Trials #7      
Gene Name #8      
Mutation #8      
Alteration Type #8      
Mutation Frequency #8     % Frequency 
Tumor Type Drugs #8      
Non-Tumor Type Drugs #8      
Clinical Trials #8      
Interacting Mutations      
Additional Mutations      
Gene Function #1      
Mutation Effect on Gene #1      
FDA Tumor Drugs #1      
FDA Non-Tumor Drugs #1      
Clinical Trials #1      
Companion Diagnostics #1      
Gene Function #2      
Mutation Effect on Gene #2      
FDA Tumor Drugs #2      
FDA Non-Tumor Drugs #2      
Clinical Trials #2      
Companion Diagnostics #2      
Gene Function #3      
Mutation Effect on Gene #3      
FDA Tumor Drugs #3      
FDA Non-Tumor Drugs #3      
Clinical Trials #3      
Companion Diagnostics #3      
Gene Function #4      
Mutation Effect on Gene #4      
FDA Tumor Drugs #4      
FDA Non-Tumor Drugs #4      
Clinical Trials #4      
Companion Diagnostics #4      
Gene Function #5      
Mutation Effect on Gene #5      
FDA Tumor Drugs #5      
FDA Non-Tumor Drugs #5      
Clinical Trials #5      
Companion Diagnostics #5      
Gene Function #6      
Mutation Effect on Gene #6      
FDA Tumor Drugs #6      
FDA Non-Tumor Drugs #6      
Clinical Trials #6      
Companion Diagnostics #6      
Gene Function #7      
Mutation Effect on Gene #7      
FDA Tumor Drugs #7      
FDA Non-Tumor Drugs #7      
Clinical Trials #7      
Companion Diagnostics #7      
Gene Function #8      
Mutation Effect on Gene #8      
FDA Tumor Drugs #8      
FDA Non-Tumor Drugs #8      
Clinical Trials #8      
Companion Diagnostics #8      
Gene Regions Passing QC      
Always Statement      
Publications      

PRIMARY
1 Tissue Paraffin Block   Room Temperature - 12 Month(s)/Refrigerated - 12 Month(s)  
2 Whole Blood EDTA 4 (2) mL   Room Temperature - 7 Day(s)/Refrigerated - 14 Day(s)  
ALTERNATE
  Micron Unstained Slides   Room Temperature - 24 Month(s)/Refrigerated - 24 Month(s)  
  DNA, extracted   Frozen - 12 Month(s)/Refrigerated - 3 Month(s)/Room Temperature - 14 Day(s)  
  H & E Slides   Refrigerated - 3 Month(s)/Room Temperature - 3 Month(s)  

This multiplex panel will allow physicians to choose the most appropriate therapy for their patients based on the alterations found in the individual's tumor sample DNA. Guidelines exist for using results from many of these genes for selection of FDA approved therapies. By testing for other genes the physician can become aware of alternative treatments available to the patient based on presence of mutations in other genes the physicians might not have considered. Additional genes indicate prognosis of those patients with mutations, thus allowing physicians and patients to choose more or less aggresive therapies. Finally, mutations found in addtional genes will qualify patients for ongoing or planned clinical trials.

Please follow Short Stability specimen process.

For tumor only, please submit FFPE (Formalin-fixed,
Paraffin-embedded), block or slides.

For paired analysis: FFPE block or slides and Whole blood must be
submitted together.

For submission of paraffin block, tumor tissue type and block ID are
required on the requisition form.

A pathology report must be submitted.

For whole blood, EDTA specimens, sample type, collection time and
date should be entered on tube and requisition form.

For paired analysis (tumor and blood), if whole blood not provided,
client services will attempt calling client to request blood. If
blood still not provided, the sample will be run from tumor only
(FFPE block or slides, or extracted DNA from tumor). Resulting will
indicate blood not submitted.

Extracted DNA: For tumor only, extracted DNA must come from FFPE
block or slides; for paired analysis extracted DNA must come from
FFPE block (or slides) and from whole blood.

Ship immediately to maintain sample stability.
Setup Schedule
Friday

Reported (Analytical Time)
14 days

CPT Code
81445

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
**This test is not available for New York patient testing.** Methodology: Next Generation Sequencing/Illumina NextSeq Transport Container: Sterile Plastic Transport Tube Transport Temperature: Room temperature Reject Criteria: Hemolysis; Baked slides Physician Attestation of Informed Consent This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.






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