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93873: Hepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes Print View
HCV RNA, QN PCR PCR    IU/mL 
HCV RNA, QN PCR PCR    LogIU/mL 

PRIMARY
1 Plasma EDTA 3 (1.8) mL   Room Temperature - 72 Hour(s)/Refrigerated - 14 Day(s)/Frozen - 42 Day(s)  
ALTERNATE
  PPT Potassium EDTA(white)   Frozen - 42 Day(s)/Room Temperature - 72 Hour(s)/Refrigerated - 14 Day(s)  
  Serum 3 (1.8) mL   Room Temperature - 72 Hour(s)/Refrigerated - 14 Day(s)/Frozen - 42 Day(s)  

A hepatitis C (HCV) viral genotype is required prior to the initiation of antiviral therapy with direct acting agents. In addition, the FDA package insert recommends baseline NS5a resistance testing for HCV genotype 1a patients being evaluated for treatment with Zepatier(TM), which contains the NS5a inhibitor elbasvir and the NS3 protease inhibitor grazoprevir. This reflex code offer clinicians the option to obtain the HCV Viral load, HCV genotype and NS5a resistance testing with a single test order when considering treatment with Zepatier(TM) or in other circumstances where all three tests are warranted.

Freshly drawn specimens (whole blood) may be stored at 2-25 degrees
centigrade for up to 24 hours prior to centrifugation. Separate plasma
or serum from cells within 24 hours of collection by centrifugation.
Follow manufacturer's instructions for collection tube handling.
Setup Schedule
Sunday-Saturday

Reported (Analytical Time)
6 days

CPT Code
87522

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Transport Temperature: Refrigerated Reject Criteria: Whole blood samples greater than 24 hours; frozen whole blood Methodology: Real-Time Polymerase Chain Reaction, Multi-Probe Reverse Hybridization; Polymerase Chain Reaction and DNA Sequencing Additional Information: If HCV RNA, PCR QN is >=300 IU/mL then Hepatitis C Viral RNA Genotype LiPA will be performed at an additional charge (CPT code(s) 87902). If HCV Genotype, LiPA is "GENOTYPE 1", "GENOTYPE 1a", or "GENOTYPE 1a OR 1b" then reflex Hepatitis C Viral RNA Genotype 1 NS5a Drug Resistance will be performed at additional charge (CPT code(s): 87902).






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