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93881: Acetylcholine Receptor Ganglionic (Alpha 3) Antibody Print View
AChR Ganglionic (Alpha3) Ab     pmol/L 

PRIMARY
1 Serum 1 (0.5) mL   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)/Frozen - 2 Month(s)  
ALTERNATE

The G-nAChR autoantibody assay can be used to identify Autoimmune Autonomic Ganglionopathy (AAG) or paraneoplastic AAG in patients with autonomic neuropathy. Identification of paraneoplastic AAG in a patient is important, as there is an association between increased levels of G-nAChR antibodies and small-cell lung cancer (SCLC) or thymoma. Detection of paraneoplastic AAG, followed by resection and/or treatment of the patients' tumor, can lead to a successful patient recovery. The G-nAChR autoantibody assay can be used as a serological diagnostic tool to differentiate patients suffering from immmunotreatment-responsive AAG from idiopathic autonomic neuropathy. Both conditions can present as acquired Autonomic Nervous System (ANS) dysfunction characterized by diffuse autonomic nervous system failure. The demonstration of AAG can lead to a focused immunological treatment and successful patient recovery. The G-nAChR antibody assay can also identify patients with limited forms of dysmotility, diabetic autonomic neuropathy, or postural tachycardia syndrome.
Setup Schedule
Wednesday

Reported (Analytical Time)
7 days

CPT Code
83519

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Radioimmunoassay Transport Temperature: Frozen Specimen Stability: Room Temperature: 48 hours Refrigerated: 48 hours Frozen: 75 days






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