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93882: Voltage-gated Calcium Channel (vgcc) Type N Antibody Print View
VGCC Type N Ab     pmol/L 

PRIMARY
1 Serum 1 (0.5) mL   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)/Frozen - 60 Day(s)  
ALTERNATE

N-type calcium channel antibodies are more highly associated with primary lung cancer than P/Q-type. One or all of the autoantibodies in the myasthenia gravis (MG)/LEMS evaluation can occur with neoplasia without evidence of neurological impairment. One or both calcium channel antibodies (P/Q and N) can occur with paraneoplastic and idiopathic cerebellar ataxia, encephalomyeloneuropathies, and autonomic neuropathy. Classsical symptoms of LEMS include proximal muscle weakness, fatigability, dry mouth and impotence. When presentation is further complicated with oculobulbar weakness, these symptoms can easily be misinterpreted as MG. However, because VGCC antibodies are positive in only approximately 5% of MG patients, the measurement of these antibodies is very useful in distinguishig LEMS from MG.
Setup Schedule
Wednesday

Reported (Analytical Time)
7 days

CPT Code
83519

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: Received room temp; freeze/thaw greater than 3 cycles; gross hemolysis; lipemic
Methodology: Radioimmunoassay
Transport Temperature: Frozen






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