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93883: Voltage-Gated Potassium Channel (VGKC) Antibody Print View
VGKC Ab     pmol/L 

PRIMARY
1 Serum 1 (0.5) mL   Room Temperature - 48 Hour(s)/Refrigerated - 48 Hour(s)/Frozen - 2 Month(s)  
ALTERNATE

Limbic encephalitis (LE) is a paraneoplastic neurological syndrome often associated with small cell lung carcinoma and more rarely with testicular, breast, and other tumors. Clinical hallmarks of paraneoplastic limbic encephalitis are changing mental status, short-term memory impairment, seizures, confusion, and behavioral changes. Hu antibody-negative LE patients usually do not develop symptoms beyond the limbic system and appear to improve more often after treatment of the cancer than those who have Hu antibodies, suggesting that the pathogenesis of the LE in both groups could be different. Recent studies have detected antibodies to voltage-gated potassium channel (VGKC) in patients with LE, with and without associated tumors. Neurologival symptoms were found to improve with a reduction of VGKC antibody levels.
Setup Schedule
Wednesday

Reported (Analytical Time)
7 days

CPT Code
83519

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Radioimmunoassay Transport Temperature: Frozen Specimen Stability: Room Temperature: 48 hours Refrigerated: 48 hours Frozen: 73 days






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