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93890: Neurology Antibody, CBA IFA Print View
NMDAR1 Ab, CBA CBA-IFA     
AMPAR1 Ab, CBA CBA-IFA     
AMPAR2 Ab, CBA CBA-IFA     
GABABR Ab, CBA CBA-IFA     
LGI-1 Ab, CBA CBA-IFA     
CASPR2 Ab, CBA CBA-IFA     

PRIMARY
1 Serum Red Top 0.5 (0.3) mL   Refrigerated - 14 Day(s)/Room Temperature - 7 Day(s)/Frozen - 21 Day(s)  
ALTERNATE
  CSF 0.5 (0.3) mL   Refrigerated - 14 Day(s)/Frozen - 21 Day(s)/Room Temperature - 7 Day(s)  

Autoantibodies to brain neurotransmitter cell surface receptors may be seen in paraneoplastic syndromes or in idiopathic autoimmune encephalitis. Antibodies to N-methyl-D-aspartate receptor (NMDAR1) may be seen in a progressive syndrome leading to behavioral changes, psychosis, seizures and coma; teratoma or other neoplasms are seen in some cases. Antibodies to voltage gates potassium channel (VGKC) is found in paraneoplastic and idiopathic autoimmune encephalopathy; in many cases, antibodies actually target VGKC-associated proteins LGI-1 or CASPR2. Antibodies to AMPAR1 and AMPAR2 are usually associated with limbic encephalitis but can present with other symptoms or psychosis, and is paraneoplastic in >50% of cases.
Setup Schedule
Wednesday, Friday

Reported (Analytical Time)
3 days

CPT Code
86255x6

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Reject Criteria: Serum separator tube

Methodology: Cell Binding Assay-Immunofluorescence Assay

Transport Temperature: Room temperature






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