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94536: Paraneoplastic Antibody Evaluation with Reflex to Titer and WB, Basic, CSF Print View
Tissue IFA Observation,CSF      
ANNA1 (Hu) Ab, IFA, CSF      
ANNA2 (Ri) Ab, IFA      
ANNA3 Ab, IFA, CSF      
PCA1 (Yo) Ab, IFA, CSF      
PCA2, Ab, IFA, CSF      
PCA-Tr (DNER) Ab, IFA,CSF      
AGNA/SOX1 Ab, IFA, CSF      
Amphiphysin Ab, IFA, CSF      
CRMP5/CV2 Ab, IFA, CSF      
GAD65 Ab, IFA, CSF      
Aquaporin-4, IFA, CSF      

PRIMARY
1 CSF 3.8 (2.4) mL   Frozen - 14 Day(s)/Refrigerated - 14 Day(s)/Room Temperature - 48 Hour(s)  
ALTERNATE

Fluorescent staining patterns on multiple neuronal and non-neuronal tissues identify likely autoantibodies present. Reflex testing to western line blot, cell based indriect immunoflurescent assay or radioimmunoassay may define specific autoantibodies.
Setup Schedule
Tuesday-Saturday

Reported (Analytical Time)
7 days

CPT Codes
86255x10,86341

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Immunoflurescence Assay Transport Temperature: Refrigerated Reflex Instructions If the paraneoplastic Ab screen, IFA is positive for Aquaporin-4 Ab, IFA, then Aquaporin-4 (AQP4) Antibody (IgG), CBA, CSF will be performed at an additional charge (CPT code(s) 86255). If Aquaporin-4 (AQP4) Antibody (IgG), CBA result is positive, then a titer will be performed at an additional charge (CPT code(s) 86256). If the Paraneoplastic Ab Screen, IFA is positive for ANNA3 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256). If the Paraneoplastic Ab Screen, IFA is positive for PCA2 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256). If the Paraneoplastic Ab Screen, IFA is indeterminate or positive for ANNA1, ANNA2, PCA1, PCA-Tr (DNER), Amphiphysin, GAD65, or CRMP5 (CV2) antibodies, then Paraneoplastic Ab, western line blot will be performed at an additional charge (CPT code(s) 84182 x7, 86341). If the Paraneoplastic Ab Screen, IFA is positive for NMDAR1, LGI-1, CASPR2, AMPAR1, AMPAR2, GABA receptor B, or Voltage Gated Antibodies, then Paraneoplastic Antibody, CBA IFA will be performed at an additional charge (CPT code(s) 86255 x6). If Paraneoplastic Antibody, CBA IFA is postive for NMDAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for AMPAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for AMPAR2 AB CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for GABA receptor B Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for LGI-1 Ab, CBA, then a titer will be per






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