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This is a sendout test. Please note that turnaround time is defined as the anticipated time from set up day to results release.
S52358: FISH, HES/Leukemia, 4q12 Rearrangement (FIP1L1-PDGFRA) [16837] Print View
FISH, HES/Leukemia 4q12 FISH     

PRIMARY
1 Bone Marrow Heparinized 3 (1) mL   Room Temperature - 72 Hour(s)  
ALTERNATE
  WB NaHep Trace Metal   Room Temperature - 72 Hour(s)  
  Tissue (Tumor Specimen)   Room Temperature - 72 Hour(s)/Frozen - 72 Hour(s)/Refrigerated - 72 Hour(s)  
  Bone Marrow Hep(Royal Bl)   Room Temperature - 72 Hour(s)  
  Bone Marrow Hep lead-free   Room Temperature - 72 Hour(s)  
  Whole Blood Heparin 5 (3) mL   Room Temperature - 72 Hour(s)  
  Whole Blood Heparin Tan 5 (3) mL   Room Temperature - 72 Hour(s)  
  Tissue Paraffin Block   Frozen - 72 Hour(s)/Refrigerated - 72 Hour(s)/Room Temperature - 72 Hour(s)  

FIP1L1-PDGFRa fusion (rearrangement of 4q12; interstitial deletion of CHIC2 region) is observed in diverse eosinophilia-associated hematologic disorders. The cases with FIP1L1-PDGFRa fusion show an excellent response to the tyrosine kinase inhibitor imatinib mesylate (Metzgeroth et al, 2007)

Bone marrow: 1-3 mL in transport medium (preferred) or
sodium heparin tube. 3-5 mL whole blood in sodium heparin tubes.
Green, dark/royal blue or tan top tubes are acceptable
containers for this test. Formalin Fixed Paraffin embedded block
and fresh tumor tissue samples are also acceptable. Ship at room
temperature. Do not freeze.
SPECIMEN VIABILITY DECREASES DURING TRANSIT. SEND
SPECIMEN TO TESTING LAB FOR VIABILITY DETERMINATION. DO
NOT REJECT.

5x5 mm Tumor tissue collected in Transport media or
5x5 mm formalin fixed paraffin embedded tissue
Setup Schedule
Sunday-Saturday

Reported (Analytical Time)
5 days

CPT Codes
88271x3,88275

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.






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