abcdefghijklmn
opqrstuvwxyz
Test Menu
Test Change Details
Allergy & Immunology
Cardiology & Coagulation
Dermatopathology
Endocrinology
Gastroenterology
Genetics
Hepatology
Infectious Disease
Microbiology
Nephrology
Neurology
Oncology
Pathology
Pediatrics
Rheumatology
Toxicology
Urology
Women's Health
This is a sendout test. Please note that turnaround time is defined as the anticipated time from set up day to results release.
S52487: PDGFRA Mutation Analysis [16859] Print View
Specimen Source      
Paraffin Block #      
PDGFRA PCR  Not detected   
Interpretation      

PRIMARY
1 Tissue Paraffin Block   Refrigerated - 12 Month(s)/Room Temperature - 12 Month(s)  
ALTERNATE
  Bone Marrow EDTA   Refrigerated - 14 Day(s)/Room Temperature - 7 Day(s)  
  Whole Blood EDTA 6 (3) mL   Room Temperature - 7 Day(s)/Refrigerated - 14 Day(s)  

Mutations in the PDGFRA gene are found in 5-8% of gastrointestinal stromal tumors (GISTs), especially in the 40-50% of KIT wild type GISTs. PDGFRA mutations also have been described in synovial sarcomas (SSs) and malignant peripheral nerve sheath tumors (MPNST). KIT and PDGFRA mutations in GISTs cause a ligand-independent autoactivation of the receptor; therefore, mutation-positive GISTs are good candidates for tyrosine kinase inhibitor treatment. GISTs with PDGFRA mutations (except D842V) are likely to respond to imatinib therapy.

For submission of whole blood: Follow standard whole blood
collection procedure. Collect 5-6 mL whole blood samples
in an EDTA tube. Blood samples are shipped at RT or 4
degrees C. Do not freeze whole blood. Record the draw
time; also record sample type on the tube and patient
ID on the requisition form. Ship immediately to maintain
sample stability.
Setup Schedule
Monday, Thursday

Reported (Analytical Time)
3 days

CPT Code
81404

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
CPT CODES: 83891,83898,83902,83912,83904(X2)






1996 - 2017 Quest Diagnostics Nichols Institute of Valencia
For test information, please call Client Services at 800-421-4449.

San Francisco Web Design & Database